Publications

Listed here are key publications, book chapters, and presentations from Seventh Street Development Group.



Books


Pharmaceutical Amorphous Solid Dispersions, 2015, Wiley and Sons, New York, edited by A. Newman, now available.

Publications

“Perspectives on the Wetting of Solids in Pharmaceutical Systems” A. Newman, G. Zografi. Pharm Res, 2023, 40, 3099–3118 (Part of the special issue in honor of Dr. Kenneth Morris, abstract)

“Commentary: Considerations in the Development of Physically Stable High Drug Load API-Polymer Amorphous Solid Dispersions in the Glassy State” A. Newman, G. Zografi. J Pharm Sci, 2023, 112, 8-18 (abstract)

“Perspective: What Are the Important Factors That Influence API Crystallization in Miscible Amorphous API-Excipient Mixtures during Long-Term Storage in the Glassy State?” A. Newman, G. Zografi. Mol. Pharm. 2022, 19, 2, 378–391 (abstract)

“Perspective: What We Need to Know about Solid-State Isothermal Crystallization of Organic Molecules from the Amorphous State below the Glass Transition Temperature” A. Newman, G. Zografi. Mol Pharm. 2020, 17, 1761–1777 (abstract)

“Commentary: Considerations in the Measurement of Glass Transition Temperatures of Pharmaceutical Amorphous Solids” A. Newman, G. Zografi. AAPS PharmSciTech, 2019, 21, 26 (free download)

“An Examination of Water Vapor Sorption by Multi-Component Crystalline and Amorphous Solids and Its Effects on their Solid-State Properties” A. Newman, G. Zografi. J Pharm Sci, 2019, 108, 1061-1080 (abstract)

“Co-Amorphous API-Small Molecule Mixtures: Considerations in the Choice of Co-Formers for Enhancing Dissolution and Oral Bioavailability” A. Newman, S. Reutzel-Edens, G. Zografi.  J. Pharm. Sci. 2018, 107, 5-17 (abstract)

“New Directions in Pharmaceutical Amorphous Materials and Amorphous Solid Dispersions, A Tribute to Professor George Zografi- Proceedings of the June 2016 Land O’Lakes Conference” A. Newman, J.E. Hastedt, M Yazdanian. AAPS Open, 2017, 3(7), 1-14 (free download)

“Interrelationships Between Structure and the Properties of Amorphous Solids of Pharmaceutical Interest” G Zografi, A. Newman. J Pharm Sci. 2017, 106, 5-27 (abstract)

“Solid Form Changes During Drug Development: Good, Bad, and Ugly Case Studies” A. Newman, R. Wenslow. AAPS Open, 2016, 2(1), 1-11 (free download)

“Drug Development- Don’t Overlook Key Preclinical Research” R. Wenslow, A. Newman. Drug Dev. Deliv2016, 16(3), 66-72 (link)

“Amorphous Solid Dispersions: A Robust Platform to Address Bioavailability Challenges”  A. Newman, K. Nagapudi, R. Wenslow. Ther. Deliv. 2015, 6,  247-261 (abstract)

“Critical Considerations for the Qualitative and Quantitative Determination of Process-Induced Disorder in Crystalline Solids” J. Pharm. Sci. 2014, 103(9), 2595-2604 (abstract).  Chosen by the editors as part of their Most Original and Most Significant Scientific Findings virtual issue.

“Specialized Solid Form Screening Techniques” A. Newman. Org. Proc. Res. Dev. 2013, 17, 457-471 (free download).

“Characterizing Miscibility in Amorphous Solid Dispersions” A. Newman, E. Munson. Amer. Pharm. Rev.2012, April, 92-98 (free download).

“Assessing the Performance of Amorphous Solid Dispersions” A. Newman, G. Knipp, G. Zografi.  J Pharm Sci .2012,101(4), 1355-1377 (abstract).

“X-ray Powder Diffraction in Solid Form Screening and Selection” A. Newman. Amer. Pharm. Rev. 2011, Sept/Oct, 44-51  (free download). 

“A Solid-state Approach to Enable Early Development Compounds: Selection and Animal Bioavailability Studies of an Itraconazole Amorphous Solid Dispersion” D. Engers, J. Teng, J. Jimenez-Novoa, P. Gent, S. Hossack, C. Campbell, J. Thomson, I. Ivanisevic, A. Templeton, S. Byrn, A. Newman. J Pharm. Sci.2010, 99(9), 3901-3922 (abstract).

“Pharmaceutical Cocrystals and Their Physicochemical Properties” N Schultheiss, A. Newman. Cryst. Growth Des., 2009, 9(6), 2950-2967 (free download).

“Characterization of Amorphous API : Polymer Mixtures Using X-ray Powder Diffraction” A. Newman, D. Engers, S. Bates, I. Ivanisevic, R. C. Kelly, G. Zografi, J. Pharm. Sci.2008, 97(11), 4840-4856 (abstract).

“Minireview: Characterization of the ‘Hygroscopic’ Properties of Active Pharmaceutical Ingredients” A. W. Newman, S. M. Reutzel-Edens, G. Zografi, J. Pharm. Sci. 2008, 97(3), 1047-1059 (abstract).

“Assessment of Defects and Amorphous Structure Produced in Raffinose Pentahydrate Upon Dehydration” S. Bates, R. Kelly, P. Schields, I. Ivanesivic, G. Zografi, A. W. Newman, J. Pharm. Sci. 2007, 96(5), 1418-1433 (abstract).

“Triboelectric Charging and Dielectric Properties of Pharmaceutically-Relevant Mixtures”D.A. Engers, M.N. Fricke, A.W. Newman, and K.R. Morris, J. Electrostat. 2007, 65, 571-581 (abstract).

“On-line Raman Spectroscopy in Pharmaceutical Process Development: Application and Future Prospects” J.K. Liang, S. Byrn, A. Newman, J. Stults, V. Smolenskaya, Amer. Pharm. Rev. 2007,10(4), 45-51.

“PAT – Process Understanding and Control of Active Pharmaceutical Ingredients” S. R. Byrn, J. K. Liang, S. Bates, Ann W. Newman, Journal of PAT 2006, 3(6), 14-19.

“Analysis of Amorphous and Nanocrystalline Solids from Their X-Ray Diffraction Patterns” S. Bates, G. Zografi, D. Engers,  K. Morris, K. Crowley, A. Newman, Pharm. Res. 2006,23(10), 2333-2349 (abstract).

“Triboelectrification of Pharmaceutically-Relevant Powders During Low-Shear Tumble Blending” D. A. Engers, M. N. Fricke, R. P. Storey, A. W. Newman, and K. R. Morris, J. Electrostat. 2006,64, 826-835 (abstract).

“Solid-state Analysis of the Active Pharmaceutical Ingredient in Drug Products”, A. W. Newman, S. R. Byrn, Drug Discovery Today 2003, 8(19), 898-905 (abstract).

“Chemical Reactivity in Solid-State Pharmaceuticals:Formulation Implications”, S. R. Byrn, W. Xu, A. W. Newman, Adv. Drug Delivery Rev.2001, 48(1), 115-136 (abstract).

“The Role of Powder X-Ray Diffraction as a Powerful Tool in Characterization of Various Hydrates of a Drug Substance”, M. Davidovich, R. Mueller , K. Raghaven, S. Ranadive, I. Vitez, B. Sarsfield, J. DiMarco, J. Gougoutas, A. Newman, Amer. Pharm. Rev.2001, 4(1), 53-60.

“The Evolution of Hot Stage Microscopy to Aid Solid State Characterizations of Pharmaceutical Solids”, I. M. Vitez, A. W. Newman, M. Davidovich, C. Kiesnowski, Thermochimica Acta 1998, 324, 187-196 (abstract).

“Physical Characterization of the Polymorphic Variations of Magnesium Stearate and Magnesium Palmitate Hydrate Species”, S. A. Sharpe, M. Celik, A. W. Newman, H. G. Brittain, Struct. Chem. 1997, 8, 73-84 (abstract).

“Quantitation of Cefepime.2HCl Dihydrate in Cefepime.2HCl Monohydrate by Diffuse Reflectance IR and Powder X-ray Diffraction Techniques”, D. E. Bugay, A. W. Newman, W.P Findlay, J. Pharm. Biomed. Anal. 1996, 15, 49-61 (abstract).

“Characterization of Humidity-Dependent Changes in Crystal Properties of a New HMG-CoA Reductase Inhibitor in Support of its Dosage Form Development”, K. R. Morris, D. E. Bugay, A. W. Newman, S. A. Ranadive, A. K. Singh, M. Szyper, S. A. Varia, H. G. Brittain, A. T. M. Serajuddin, Int. J. Pharm. 1994, 108, 195-206 (abstract).

“An Integrated Approach to the Selection of Optimal Salt Form for a New Drug Candidate”,  K. R. Morris, M. G. Fakes, A. B. Thakur, A. W. Newman, A. K. Singh, J. J. Venit, C. J. Spagnuolo, A. T. M. Serajuddin, Int. J. Pharm. 1994, 105, 209-217 (abstract).

“Factors Affecting Differences in Film Thickness of Beads Coated in Fluidized Bed Units”, R. Wesdyk, Y. M. Joshi, J. DeVincentis, A. Newman, N. B. Jain, Int. J. Pharm. 1993, 93, 101-109 (abstract).

“Physical Interactions of Magnesium Stearate with Starch-Derived Disintegrants and Their Effects on Capsule and Tablet Dissolution”, D. S. Desai, B. A Rubitski, S. A. Varia, A. W. Newman, Int. J. Pharm.1993, 91, 217-226 (abstract)

“Changes in Material Properties Accompanying the NF Identity Test for Microcrystalline Cellulose”, H. G. Brittain, G. Lewen, A. W. Newman, K. Fiorelli, S. Bogdanowich, Pharm. Res.1993, 10(1), 61-67 (abstract)

“Physical Characterization of Pharmaceutical Solids”, H. G. Brittain, S. J. Bogdanowich, D. E. Bugay, J. DeVincentis, G. Lewen, A. W. Newman, Pharm. Res.1991,8(8), 963-973 (abstract).

“The Effect of Size and Mass on Film Thickness of Beads Coated in Fluidized Bed Equipment”, R. Wesdyk, N. Jain, Y. M. Yoshi, K. Morris, A. Newman, Int. J. Pharm. 1990, 65, 69-76 (abstract).


Book Chapters

“Hygroscopicity and Hydrates in Pharmaceutical Solids”, S.M. Reutzel-Edens, D.E. Braun, A.W. Newman in Polymorphism in the Pharmaceutical Industry: Solid Form and Drug Development, Wiley, Weinheim,  2019, 159-188.

“Solid-state Characterization Techniques” A. Newman, R. Wenslow in Pharmaceutical Crystals: Science and Engineering, Wiley, New York, 2018, 89-121.

“Salt and Cocrystal Screening”  A. Newman, C. Chen, C. Sanrame in Early Drug Development: Bringing a Preclinical Candidate to the Clinic, Wiley, New York, 2018, 229-270.

“Rational Design for Amorphous Solid Dispersions” A. Newman in Developing Solid Oral Dosage Forms, 2nd Edition, Academic Press, New York, 2017, 497-518.

“Introduction to Amorphous Solid Dispersions” G. Zografi, A. Newman in Pharmaceutical Amorphous Solid Dispersions, Wiley, New York, 2015, 1-41.

Amorphous Solid Dispersion Screening” A. Newman in Pharmaceutical Amorphous Solid Dispersions, Wiley, New York, 2015,  85-116.

“States of Matter Related to Pharmaceutical Formulations” B.J. Sandman, edited by A. Newman, G. T. Knipp. in Applied Physical Pharmacy, 2nd Edition, McGraw Hill Education, New York, 2014,  15-39.

“Salt Cocrystal Form Selection” Chapter 14, A. W. Newman, S. L. Childs, B. A. Cowans, in Preclinical Development Handbook, John Wiley and Sons, Hoboken,2008, 455-481.

“Thermal Microscopy” I. M. Vitez, A. W. Newman, in Thermal Analysis of Pharmaceuticals, CRC Press, Boca Raton, 2007, 221-264.

“The Physical Characterization of Hygroscopicity in Pharmaceutical Solids” S. M. Reutzel-Edens and A. W. Newman, in Polymorphism in the Pharmaceutical Industry, Wiley-VCH, Weinheim, 2006, 235-258.

“Form Selection of Pharmaceutical Compounds”, A. W. Newman and G.P. Stahly, in Handbook of Pharmaceutical Analysis, Marcel Dekker, New York, 2002, vol 117, 1-57.

“Sorbitol”, A.W. Newman, I.M. Vitez, R.L. Mueller, C. Kiesnowski, M. Davidovich, W.P. Findlay, Analytical Profiles of Drug Substances and Excipients, Academic Press, New York, 1999, vol. 26, 459-502.

“Starches and Starch Derivatives”, A.W. Newman, I.M. Vitez, C. Kiesnowski, R. Mueller, in Encyclopedia of Pharmaceutical Technology, Marcel Dekker, New York, 1996, vol. 14, 223-248.

“Starch, A.W. Newman, I.M. Vitex, C. Kiesnowski, R. Mueller, D.E. Bugay, W.P. Findlay, C. Rodriguez, in Analytical Profiles of Drug Substances and Excipients, Academic Press, New York, 1996vol. 24, 523-578.

“Particle Morphology: Optical and Electron Microscopies”, A.W. Newman and H.G. Brittain, in Physical Characterization of Pharmaceutical Solids, H.G. Brittain, Ed., Marcel Dekker, New York, 1995, 127-156.

“Micromeretics”, A.W. Newman and H.G. Brittain, in Physical Characterization of Pharmaceutical Solids, H.G. Brittain, Ed., Marcel Dekker, New York, 1995, 253-280.

“Talc”, A.W. Newman, I.M. Vitez, P. Cortina, G. Young, J. DeVincentis, D.E. Bugay, T. Patel, AnalyticalProfiles of Drug Substances and Excipients, Academic Press, New York, 1994vol. 23, 511-542.

“Titanium Dioxide”, H.G. Brittain, G. Barbera, J. DeVincentis, A.W. Newman, in AnalyticalProfiles of Drug Substances and Excipients, Academic Press, New York, 1992vol. 21, 659-691.

“Anhydrous Lactose”, H.G. Brittain, S.J. Bogdanowich, D.E. Bugay, J. DeVincentis, G. Lewen, A.W. Newman, AnalyticalProfiles of Drug Substances and Excipients, Academic Press, New York, 1991vol. 20, 369-398.


Invited Presentations

“Using Thermal Analysis to Characterize Amorphous Pharmaceutical Materials”, A. Newman, invited talk at Rigaku Pharmalytical Summit, Virtual Conference, May 2021.

“Amorphous Solid Dispersions: Screening, Selection, and Scale-up” A. Newman, invited talk at University of Wisconsin-Madison Professional Development Course on Understanding, Characterizing, and Developing Amorphous Materials and Amorphous Solid Dispersions, Madison WI, May 2018.

Coamorphous Materials: What Are They and Are They Developable” A. Newman, invited talk at Northeast Regional Discussion Group (NERDG) Meeting, Farmington CT, April 2018.

“Process Induced Transformations: Why is My Form Changing?” A. Newman, invited talk at June Land O’Lakes Conference, University of Wisconsin Annual International Industrial Pharmaceutical Research and Development Conference on Material Sciences Based Approaches to Improving Drug Delivery Performance: From Discovery Through Manufacturing, Madison WI, June 2017.

“Amorphous Basics and Preparation of Amorphous Solids” A. Newman, invited talk at Amorphous Solids Short Course at Denver X-Ray Conference, Chicago IL, August 2016.

“Amorphous Solid Dispersions: Screening, Selection, and Scale-up” A. Newman, invited talk at University of Wisconsin-Madison Professional Development Course on Understanding, Characterizing, and Developing Amorphous Materials and Amorphous Solid Dispersions, Madison WI, May 2016.

“Using Polymorph Screening Information to Develop a Crystallization Process” A. Newman, invited talk at Scientific Update Process Development Conference, Barcelona Spain, September 2015.

“Amorphous Solid Dispersions: Screening, Selection, and Scale-up” A. Newman, invited talk at University of Wisconsin-Madison Professional Development Course on Understanding, Characterizing, and Developing Amorphous Materials and Amorphous Solid Dispersions, Madison WI, May 2015.

“XRPD to Characterize Disordered and Amorphous Pharmaceutical Samples” A. Newman, invited talk at IUCr 2014, Montreal, August 2014.

“Amorphous Solid Dispersions: Screening, Selection, and Scale-up” A. Newman, invited talk at University of Wisconsin-Madison Professional Development Course on Understanding, Characterizing, and Developing Amorphous Materials and Amorphous Solid Dispersions, Madison WI, April 2014.

“Form Screening and Selection” A. Newman, invited talk at the American Chemical Society (ACS) ProSpectives 2013 International Conference on Pharmaceutical Solid State Research: Form, Function, Formulation, Suzhou China, October 2013.

“Case Studies on Solid Form Changes During Development” A. Newman, invited talk at Scientific Update Conference on Organic Process Research and Development, Clearwater, FL, March 2013.

“Making Amorphous API”  A. Newman, invited talk at the Understanding Pharmaceutical Amorphous Materials Workshop, 11th Pharmaceutical Powder Diffraction X-Ray Diffraction Symposium (PPXRD-11), Fort Myers, FL, May 2012 (slides).

“Using Thermal Techniques for Amorphous Materials”  A. Newman, invited talk at the Understanding Pharmaceutical Amorphous Materials Workshop, 11th Pharmaceutical Powder Diffraction X-Ray Diffraction Symposium (PPXRD-11), Fort Myers, FL, May 2012 (slides).

“Quantifying Low Level Amorphous Content” A. Newman, invited talk at Almac and University of Cork Joint Workshop: Quantitative Analytical Methods for the Solid State, Cork, Ireland, March 2012.

“Amorphous Dispersion Overview: Challenges and Opportunities” A. Newman, invited talk at ExL Pharma Enhancing Drug Bioavailability and Solubility Workshop on Assessing Technologies for Efficient Development of Amorphous Solid Dispersions, Boston, MA, January 2012.

“Solid Form Screening and Selection During Development” A. Newman, invited talk at CrystEngComm Pharmaceutical Polymorphism Symposium, London, UK, November 2011.

“Solid State Chemistry of Biopharmaceuticals: Fundamental Issues and Study Approaches” A. Newman, S. Byrn, S. Bogdanowich-Knipp, H. Zhang, R. Von Dreele, invited talk at Asian Arden House, Seoul, South Korea, June 2011.

“An Overview of Solid Form Screening During Drug Development” A. Newman, invited talk at 10th Pharmaceutical Powder X-Ray Diffraction Symposium (PPXRD-10), Lyons France, May 2011 (slides).

“Amorphous Basics”  A. Newman, invited talk at the Understanding Pharmaceutical Amorphous Materials Workshop, 10th Pharmaceutical Powder Diffraction X-Ray Diffraction Symposium (PPXRD-10), Lyons France, May 2011.

“Making Amorphous API”  A. Newman, invited talk at the Understanding Pharmaceutical Amorphous Materials Workshop, 10th Pharmaceutical Powder Diffraction X-Ray Diffraction Symposium (PPXRD-10), Lyons France, May 2011.

“Using Thermal Techniques for Amorphous Materials”  A. Newman, invited talk at the Understanding Pharmaceutical Amorphous Materials Workshop, 10th Pharmaceutical Powder Diffraction X-Ray Diffraction Symposium (PPXRD-10), Lyons France, May 2011.

“Case Study: Physical Chemical Properties-Changes During Development” A. Newman, invited talk at June Land O’Lakes Conference, 52nd Annual International Industrial Pharmaceutical Research and Development Conference on Science-Driven Drug Product Development Strategies to Achieve Proof of Concept, Merrimac, June 2010.

“Drug Product Characterization: What Form Do I Have?” A. Newman, invited talk at 9th Pharmaceutical Powder X-Ray Diffraction Symposium (PPXRD-9), Hilton Head, February 2010.

“Basics of Amorphous and Amorphous Solid Dispersions”, A. Newman, invited talk at the Understanding Pharmaceutical Amorphous Materials Workshop, 9th Pharmaceutical Powder Diffraction X-Ray Diffraction Symposium (PPXRD-9), Hilton Head, February 2010 (slides).

“Role of Solid Forms in Lifecycle Management” A. Newman and J. Hastedt, invited workshop at Pharma IQ’s  8th Annual Polymorphism and Crystallization Scientific Forum, Philadelphia, October 2009.

“Form Selection to Improve Solubility” A. Newman, invited talk at Pharma IQ’s 4th Annual Improving Solubility Conference 2008, London, June 2008.

“Comprehensive Approach to Form Screening” A. W. Newman, invited talk at Polymorphism and Crystallization Scientific Forum, Philadelphia, September 2005.

“Amorphous and Disordered Pharmaceutical Materials” S. Bates and A.W. Newman, invited workshop at Polymorphism and Crystallization Scientific Forum, Philadelphia,  September 2005.

“Process-Induced Transformations” A. W. Newman, invited presentation at Polymorphism, Crystallization and Salt Selection Conference, Washington, DC, February 2005.

“Cocrystallization as a Feasible Method of Solid Form Screening” S. Childs and A. W. Newman, invited workshop at Polymorphism, Crystallization and Salt Selection Conference, Washington, DC, February 2005.

“Process Analytical Technology (PAT): Achieving Mechanistic Understanding through Solid-State Chemistry” S. R. Byrn and A. W. Newman, invited workshop at Polymorphism, Crystallization and Salt Selection Conference, Washington, DC, February 2005.

“Analysis of Short-range Order in X-ray Amorphous Indomethacin Using X-ray Powder Diffraction and Pair-Wise Distribution Functions” A. W. Newman, S. Bates, G. Zografi, K. Crowley, invited presentation at Preformulation/Formulation Strategies Conference, Philadelphia, February 2005.

“Trouble Shooting Phase Transitions During Processing”, A. W. Newman, invited presentation at Polymorphism and Crystallization Forum, Princeton, April 2004.

“An Overview of Form Selection”, Form Selection for Pharmaceutical Systems Workshop, A. W. Newman, invited presentation at Polymorphism and Crystallization Forum, Princeton, April 2004.

“A Tiered Approach to Salt and Cocrystal Selection”, A. W. Newman, invited presentation at Salt Selection and Formulation /Preformulation Strategies, Philadelphia, March 2004.

“Commonly Used Techniques to Characterize Phase Transitions During Processing”, A. W. Newman, invited presentation at AAPS Annual Meeting, Toronto, November 2002.

“SSCI and MSI Joint Venture”, A. W. Newman, invited talk at Molecular Simulations Inc. Pharmaceutical Development Consortium Meeting, March 1999.

“The Effect of Particle Size at Various Stages of Pharmaceutical Manufacturing: Using Traditional and Non-Traditional Techniques”, A. W. Newman, J. DeVincentis, G. Lewen, D. Bergman, K. Fiorelli, S. J. Bogdanowich invited talk at Fine Particle Society 23rd Annual Meeting, July 1992.

 


Professional Presentations

“Screening and Animal Bioavailability Studies on Itraconazole Amorphous Dispersions” D. Engers, J. Teng, J. Jimenez-Novoa, P. Gent, S. Hossack, C. Campbell, J. Thomson, I. Ivanisevic, A. Templeton, S. Byrn, A. W. Newman at AAPS, Atlanta, November 2008.

“Computational Studies of API:Polymer Mixtures From X-ray Powder Diffraction Data” S.Bates, I. Ivanisevic, P. Chen, D. Engers, R. Kelly, A. Newman, G. Zografi at 6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Barcelona, Spain, April 2008.

“Characterization of API:Polymer Mixtures using X-ray Powder Diffraction” S. Bates, R. Kelly, D.Engers, G. Zografi, A. Newman at AAPS, San Diego, November 2007.

“Analysis of Process Induced Defects in Pharmaceutical Solids”  S. Bates, P. Schields, I. Ivanisevic, R. Kelly, G. Zografi, A. W. Newman at  AAPS Annual Meeting, San Antonio, October 2006.

“In-situ Monitoring of a Drying Process for a Complex Hydrate API using Raman Spectroscopy”  J. K. Liang, A. W. Newman, J. Stults, V. Smolenskaya at  AAPS Annual Meeting, Nashville, November 2005.

“Relationship Between Triboelectric Charge and Dielectric Response in Binary Mixtures Containing Metal Stearates” D. A. Engers, M. W. Nowling, A. W. Newman, and K. R. Morris at Purdue-Michigan Program for the Study of Supramolecular Assemblies and Solid-State Properties, West Lafayette, IN, September 2005.

“Pair-Distribution Functions: Probing the Evolution of Microstructure in Amorphous Pharmaceutical Materials”  D. A. Engers, K. R. Morris, G. Zografi, A. W. Newman, S. Bates at Midwest Organic Solid State Chemistry Symposium XVI, West Lafayette, June 2005.

“Polymorph and Crystallization Studies of dOTC”, A. W. Newman, M. C. Andres, G. P. Stahly, A. Cimpoia at AAPS Annual Meeting, Toronto, November 2002.

“Quantitation of dOTC Form A in Drug Product Using X-Ray Powder Diffraction”, A. W. Newman, M. C. Andres, A. Cimpoia at AAPS Annual Meeting, Toronto, November 2002.

“Unsolvated Enantiotropic Polymorphs of Loperamide Hydrochloride”, A. W. Newman, M. C. Andres, G. P. Stahly, L. Ohannessian, A. Adair at AAPS Annual Meeting, Toronto, November 2002.

“Quantitation of Two Polymorphic Forms Using Rietveld Analysis, Synchrotron X-Ray Powder Diffraction, and Traditional X-Ray Powder Diffraction,” A. W. Newman, H. Morrison, M. Andres, G. Stahly, A. Thomas, P. Stephens at First Annual International Workshop on Physical Characterization of Pharmaceutical Solids, Lancaster, PA, September, 2000.

“The Role of Powder X-ray Diffraction as a Powerful Tool in the Characterization of Various Hydrates of a Drug Substance,” M. Davidovich, J. DiMarco, J. Gougoutas, R, Mueller, A. Newman, K. Raghavan, S. Ranadive, I. Vitez, B. Sarsfield at First Annual International Workshop on Physical Characterization of Pharmaceutical Solids, Lancaster, PA, September, 2000.

“Use of Variable Temperature Assays to Study the Physical Properties of a Solid Bulk Drug Substance,” I. M. Vitez, M. Davidovich,  W. P. Findlay, M. Galella, G. McGeorge, R. L. Mueller, A. W. Newman, B. Sarsfield at the 39th Eastern Analytical Symposium, Somerset, November, 1999.

“Quantitation of Two Polymorphic Forms Using X-Ray Powder Diffraction and Rietveld Analysis”, A. W. Newman, P. Stephens, H. G. Morrison, M. C. Andres, A. S. Thomas, G. P. Stahly at AAPS Annual Meeting, November 1999.

“Quantitation of Amorphous Material in Micronized Levalbuterol Sulfate”, Paul McGlynn, Martin P. Redmon, Stephen A. Wald, Henry G. Morrison, Ann W. Newman, Brenton W. Russell, G. Patrick Stahly, David E. Bugay, Li Li-Bovet, and Agustin F. Venero  at AAPS Annual Meeting, November 1999.

“Quantitation of Two Polymorphic Forms Using Rietveld Analysis, Synchrotron X-ray Powder Diffraction, and Traditional X-ray Powder Diffraction” A. W. Newman, P. W. Stephens, M. C. Andres, G. P. Stahly, H. G. Morrison, A. S. Thomas at ICDD Pharmaceutical Symposium, September 1999.

“Crystal Form Quantitation Using Rietveld Analysis”, A. W. Newman, M. C. Andres, M. C. Wahle at Molecular Simulations Inc. Pharmaceutical Development Consortium Meeting, March 1999.

“Analysis of Pharmaceutical Pick-Up Sticks Using Digital Thermal Video Microscopy”, I. M. Vitez, A. W. Newman, M. Davidovich, R. L. Mueller at Eastern Analytical Symposium and Exposition, November 1998.

“Physical Characterization of a Solid Bulk Drug Substance Using a Multi-Disciplinary Approach”, I. M. Vitez, W. P. Findlay, M. Gallela, R. L. Mueller, A. W. Newman, B. Sarsfield, and A. K. Swensen at Eastern Analytical Symposium and Exposition, November 1998.

“Solving Characterization Problems in the Solid State using CERIUS2”, A. W. Newman, I. M. Vitez, M. Davidovich, R. L. Mueller, K. R. Morris at Molecular Simulations Inc. Materials Characterization Seminar, September 1998.